{"id":15899,"date":"2024-05-04T18:41:27","date_gmt":"2024-05-04T15:41:27","guid":{"rendered":"https:\/\/cmcpal.com\/site\/?post_type=product&#038;p=15899"},"modified":"2024-05-04T18:42:29","modified_gmt":"2024-05-04T15:42:29","slug":"tm-ca-72-4-ref-hye-5382","status":"publish","type":"product","link":"https:\/\/cmcpal.com\/site\/product\/tm-ca-72-4-ref-hye-5382\/","title":{"rendered":"TM-CA 72-4 \/ REF: HYE-5382"},"content":{"rendered":"<div><a href=\"https:\/\/cmcpal.com\/site\/wp-content\/uploads\/2024\/05\/HYE-5382.pdf\"><img decoding=\"async\" class=\"alignnone wp-image-14297\" src=\"https:\/\/cmcpal.com\/site\/wp-content\/uploads\/2024\/04\/file-pdf-300x300.png\" alt=\"\" width=\"64\" height=\"64\" srcset=\"https:\/\/cmcpal.com\/site\/wp-content\/uploads\/2024\/04\/file-pdf-300x300.png 300w, https:\/\/cmcpal.com\/site\/wp-content\/uploads\/2024\/04\/file-pdf-200x200.png 200w, https:\/\/cmcpal.com\/site\/wp-content\/uploads\/2024\/04\/file-pdf-150x150.png 150w, https:\/\/cmcpal.com\/site\/wp-content\/uploads\/2024\/04\/file-pdf.png 512w\" sizes=\"(max-width: 64px) 100vw, 64px\" \/><\/a><\/div>\n<div>\n<div class=\"row\">\n<div class=\"col-xl-10 mx-auto\">\n<div id=\"myTabContent\" class=\"tab-content\">\n<div id=\"description\" class=\"tab-pane fade show active\" role=\"tabpanel\" aria-labelledby=\"description-tab\">\n<div class=\"p-3 p-md-5\">\n<h2><strong>TM-CA 72-4\u00a0<\/strong><\/h2>\n<div>\nThe DRG CA 72-4 CLIA is a chemiluminescence immunoassay for the quantitative in vitro diagnostic measurement CA 72-4 in serum and plasma<\/p>\n<p>CA 72-4 (Cancer antigen 72-4) was originally described as an antigenic determinant recognized by B 72.3, a<br \/>\nmurine monoclonal antibody raised against a membrane extract of mamacarcinoma metastases (1). CA 72-4<br \/>\nwas identified as a 1 MDa mucine-like Glycoprotein complex termed TAG-72 (tumor associated antigen 72)<br \/>\n(2). The molecular weight of the TAG-72 protein is 48 kD. Elevated CA 72-4 levels in serum and plasma<br \/>\nhave been reported in various malignant diseases including carcinomas of pancreas, stomach, gall, colon,<br \/>\nmamma, ovaries, cervix and endometrium (3). The highest diagnostic sensitivities are found for carcinomas<br \/>\nof the gastrointestinal tract and ovaries. Although some benign diseases such as rheumatic diseases or<br \/>\novary cysts may also result in elevated levels of CA 72-4, clinical studies demonstrated diagnostic<br \/>\nspecificities of more than 95% for gastrointestinal and ovarian malignancies (4). There is a good correlation<br \/>\nbetween CA 72-4 levels and tumor stage and size (3). CA 72-4 is the marker of choice for the therapeutic<br \/>\nmonitoring and follow-up care of gastrointestinal cancer patients. Suitable second markers are CA 19-9 or<br \/>\nCEA. Additionally, CA 72-4 has been used as an independent marker for the therapeutic monitoring and<br \/>\nfollow-up care of ovarian cancer patients, in particular in CA 125 negative patients<\/p><\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>TM-CA 72-4\u00a0 The DRG CA 72-4 CLIA is a chemiluminescence immunoassay for the quantitative in vitro diagnostic measurement CA 72-4 in serum and plasma CA 72-4 (Cancer antigen 72-4) was originally described as an antigenic determinant recognized by B 72.3, a murine monoclonal antibody raised against a membrane extract of mamacarcinoma metastases (1). CA 72-4&hellip;<\/p>\n","protected":false},"featured_media":15900,"comment_status":"open","ping_status":"closed","template":"","meta":[],"pwb-brand":[167],"product_brand":[],"product_cat":[147,135,111,118],"product_tag":[],"class_list":{"0":"post-15899","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"pwb-brand-drg","7":"product_cat-clia-drg","8":"product_cat-drg","9":"product_cat-laboratory","10":"product_cat-reagents","11":"description-off","13":"first","14":"instock","15":"shipping-taxable","16":"product-type-simple"},"brands":[{"id":167,"name":"DRG","slug":"drg"}],"_links":{"self":[{"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/product\/15899","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/comments?post=15899"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/media\/15900"}],"wp:attachment":[{"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/media?parent=15899"}],"wp:term":[{"taxonomy":"pwb-brand","embeddable":true,"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/pwb-brand?post=15899"},{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/product_brand?post=15899"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/product_cat?post=15899"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/cmcpal.com\/site\/wp-json\/wp\/v2\/product_tag?post=15899"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}